Principal signaling receptor is Frizzled (Fz), contains 

7 TM α helices.

TLS Online TPP Program

#Id: 8054

#Unit 1. Molecules and their Interaction Relevant to Biology

TLS Online TPP Program

#Id: 8055

#Unit 1. Molecules and their Interaction Relevant to Biology

TLS Online TPP Program

#Id: 8056

#Unit 1. Molecules and their Interaction Relevant to Biology

Glu–Cys–Gly peptide in which the γ-carboxylate group of the glutamate side chain forms an isopeptide bond.

TLS Online TPP Program

#Id: 8057

#Unit 1. Molecules and their Interaction Relevant to Biology

Cysteine, tryptophan, and methionine are not common amino acids: together, they constitute approximately 5 percent of the amino acids in a typical protein. Four amino acids—leucine, serine, lysine, and glutamic acid—are the most abundant amino acids, constituting 32 percent of all the residues in a typical protein.

TLS Online TPP Program

#Id: 8058

#Unit 1. Molecules and their Interaction Relevant to Biology

Aspartate: P type ATPase and two component signalling.

Asparagine: N linked Glycosylation.

Cysteine- Fd-Trx system, PDI, G3PD, Hh, 

TLS Online TPP Program

#Id: 8059

#Unit 1. Molecules and their Interaction Relevant to Biology

Glycine: Most conserved, G12 Ras, RGD, FG, 

Glutamine: NPQ, CAG repeat

GlutamatE: Neurotransmitter, VGLUT, Calmodulin, Nitrogen Assimilation