FOXP1 is a transcription factor which stimulate the production of Oct4 and Nanog and establish pluripotency. Which of the following statements are correct regarding to the mechanism of alternative splicing of FOXP1. 

A. There are two isoforms of the FoxP1 protein, One is the product of an mRNA spliced to include a particular exon, 18b, while the other splicing variant carries exon 18a.

B. When alternative splicing generates a form including exon 18b in place of 18a, the resulting isoform (FOXP1-ES) binds to a different DNA sequence and thus controls expression of a different set of genes.

C. The protein encoded by the exon 18b– carrying mRNA is called FOXP1-ES it fails to stimulate expression of OCT4 and NANOG and instead actives genes that promote differentiation. 

D. The exon 18a– containing form encodes FOXP1 itself, and this has the opposite effect: this activates genes that promote dedifferentiation, and thus stimulates iPS cell formation.

#Question id: 9159

#Unit 9. Diversity of Life Forms

Which of the following investigations would shed the most light on the future distribution of organisms in temperate regions that are faced with climate change?

#Question id: 9160

#Unit 9. Diversity of Life Forms

Generally speaking, deserts are located in places where air masses are usually ________.

#Question id: 9161

#Unit 9. Diversity of Life Forms

When climbing a mountain, we can observe transitions in biological communities that are analogous to the changes ________.

#Question id: 9162

#Unit 9. Diversity of Life Forms

If the direction of Earth's rotation reversed, the most predictable effect would be ________.

#Question id: 9163

#Unit 9. Diversity of Life Forms

Use the following figures to answer the question below

Based on the data in the figures, which of the following statements are correct?

I) Area 1 would be considered a desert because of its high average temperature.

II) Area 1 has more average precipitation than Area 2.

III) Area 2 would be considered a desert because of its low average precipitation.

IV) Area 2 has a larger annual temperature variation.

#Question id: 9164

#Unit 9. Diversity of Life Forms

Use the following figures to answer the question below.

East of the Mississippi River, in Hopkinsville Kentucky, the mean annual precipitation is 130 cm. The mean annual temperature is 14.3°C. In the winter, the mean temperature is 7.3°C, while in summer it is 20.6°C. Using the climograph shown here, how would we classify the biome found in Hopkinsville?