The cytochrome P450 constitute a superfamily of heme-containing enzymes that occur in nearly all living organisms, from bacteria to mammals, These monooxygenases, which in animals are embedded in the endoplasmic reticulum membrane, catalyze reactions of the sort

                  RH + O₂ + 2 H⁺ + 2e⁻ → ROH + H₂O 

The electrons (e−) are supplied by NADPH, which passes them to cytochrome P450’s heme prosthetic group via the intermediacy of the enzyme NADPH P450 reductase. Here RH represents a wide variety of usually lipophilic compounds for which the different cytochromes P450 are specific. They include

a. polycyclic aromatic hydrocarbons 

b. polycyclic biphenyls

c. frequently carcinogenic compounds that are present in tobacco smoke, broiled meats, and other pyrolysis products

d. which were widely used in electrical insulators and as plasticizers and are also carcinogenic.

TLS Online TPP Program

#Question id: 33527

#Unit 2. Cellular Organization

Match the following

TLS Online TPP Program

#Question id: 33528

#Unit 2. Cellular Organization

The Y chromosome has 

TLS Online TPP Program

#Question id: 33529

#Unit 2. Cellular Organization

A. X and Y chromosomes have descended from a common, very ancient autosome pair. 

B. X and Y chromosomes have descended from different autosome. 

C. During evolution, the X chromosome has retained most of the original genes, whereas the Y chromosome has lost most of them.

D. During evolution, the X chromosome has lost most of them, whereas the Y chromosome has retained most of the original genes.

Which of the following is correct combination

TLS Online TPP Program

#Question id: 33530

#Unit 2. Cellular Organization

One approach to determine the number of essential genes

A. Mutational Analysis

B. Sequence Alignments

C. Complementation

D. Mass Spectroscopy

TLS Online TPP Program

#Question id: 33531

#Unit 2. Cellular Organization

The data obtained during DNA microarray analysis showing wildtype vs. mutant expression of genes under different conditions, represented as

TLS Online TPP Program

#Question id: 33691

#Unit 2. Cellular Organization

Pseudogenes