#Question id: 2990
#Unit 2. Cellular Organization
Mitotic CDK complexes are maintained in an inactive state through inhibitory phosphorylation of the CDK subunit. Two highly conserved tyrosine and threonine residues in mammalian CDKs are subject to regulated phosphorylation.
|
Gene |
Mutant phenotypes |
|
A. Wee1 |
i. the cell does not divide but continues to grow |
|
B. CAK kinase |
ii. mitotic cyclins are inactivated |
|
C. cdc25 phosphatase |
iii. premature entry into mitosis |
The following table enlists genes and phenotypes observed on mutation of these genes but not correctly matched. Which one of the following combinations is correctly matched ?
#Question id: 2991
#Unit 2. Cellular Organization
Early observations of a cultured cell line indicated that the cells did not exhibit either density-dependent inhibition or anchorage dependence. What do these observations suggest about this cell line?
#Question id: 2992
#Unit 2. Cellular Organization
DNA was isolated from three different cell types of the same organism, the relative DNA content for each type was determined, and the results were plotted on the graph shown in the figure below. Refer to the graph to answer the following questions. Which sample of DNA might be from a cell that stopped the process of cell division in G0 phase of the cell cycle prior to meiosis?
#Question id: 2993
#Unit 2. Cellular Organization
During meiosis, a defect occurs in a cell that results in the failure of spindle microtubules binding at the kinetochores. Which of the following statements describes the most likely result of such a defect?
#Question id: 2994
#Unit 2. Cellular Organization
If a cell has completed meiosis I and the first cytokinesis, and is just beginning meiosis II, which of the following is an appropriate description of its genetic contents?
#Question id: 4718
#Unit 2. Cellular Organization
All the following statements about destruction of cyclins are true, except: