TLS Online TPP Program

#Question id: 15445


Necroptosis, 
Choose INCORRECT statements about this ?

#Unit 4. Cell Communication and Cell Signaling
  1. Which occurs only in the absence of caspase-8, would provide an alternative pathway for cell death that also prevents pathogen spread, but at a cost to the host organism—inflammation.
  2. TNFα triggered necroptosis rather than apoptosis.
  3. A series of interactions leads to the recruitment of the kinases RIPK1 and RIPK3, which are thought to oligomerize into a structure dubbed the necrosome, and the activation of RIPK3 kinase activity.
  4. MLKL, is a substrate for RIPK3, is targeted to the plasma membrane before its phosphorylation.