You have isolated two temperature-sensitive mutations in phage l that you suspect may be in the same gene. These phage mutants are called ts-1 and ts-2. Each mutant will form plaques at 35˚C but not at 42˚C. You cross ts^-1 to ts^-2 phage by coinfecting E. coli at the permissive temperature of 35˚C. When the resulting phage lysate is plated at 35˚C you count 10,000 plaques per ml of phage lysate, but when the same phage lysate is plated at 42˚C, there are only 80 plaques per ml.  

If the total size of the phage is 5 x 10⁴ bp and the total genetic map length of the phage is 100 m.u., about how far apart are the mutations in base pairs?

TLS Online TPP Program

#Question id: 28730

#Unit 2. Cellular Organization

A proteins containing a Tyr-X-X-Φ sequence bind to Vesicles coated with which of the following protein?

TLS Online TPP Program

#Question id: 28731

#Unit 2. Cellular Organization

For selective export of certain membrane proteins from the ER to Golgi contain___

TLS Online TPP Program

#Question id: 28732

#Unit 2. Cellular Organization

A proteins containing a Tyr-X-X-Φ sequence bind to Vesicles coated with_____

TLS Online TPP Program

#Question id: 28733

#Unit 2. Cellular Organization

Vesicles coated with GGA proteins and clathrin bind to proteins containing___

TLS Online TPP Program

#Question id: 28734

#Unit 2. Cellular Organization

Which of the following an ER membrane protein that acts as a cargo receptor for collagen?

TLS Online TPP Program

#Question id: 28735

#Unit 2. Cellular Organization

Most common CFTR mutation is a ΔF508 causes_

a)Changing the conformation of the cytosolic portion of CFTR so that the signal is unable to bind to Sec24

b)Changing the conformation of the cytosolic portion of CFTR so that the signal is unable to bind to Sec23

c)blocking its packaging into COPII vesicles budding from the ER

d)blocking its packaging into COPI vesicles budding from the ER

Which of the following is correct result of mutated CFTR?