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TLS Online TPP Program

#Question id: 1509

Cells that are infected, damaged, or have reached the end of their functional life span often undergo "programmed cell death." This controlled cell suicide is called apoptosis. Select the appropriate description of this event on a cell's life cycle.

#Unit 4. Cell Communication and Cell Signaling

  1. Apoptosis is regulated by cell surface receptors that signal when a cell has reached its density-dependent limits.

  2. During apoptosis, dying cells leak out their contents, including digestive enzymes that also destroy healthy cells.

  3. During apoptosis, cellular agents chop up the DNA and fragment the organelles and other cytoplasmic components of a cell.

  4. Each cell organelle has protein signals that initiate the breakdown of the organelle's components, which leads to cell death.

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TLS Online TPP Program

#Question id: 30106

#Unit 1. Molecules and their Interaction Relevant to Biology

If a cell has an adequate supply of adenine nucleotides but requires more guanine nucleotides for protein synthesis:

1. Glutamine-PRPP amidotransferase will not be fully inhibited.
2. AMP will be a feedback inhibitor of the condensation of IMP with aspartate.
3. ATP will stimulate the production of GMP from IMP.
4. ATP will inhibit nucleoside diphosphate reductase.
TLS Online TPP Program

#Question id: 30107

#Unit 1. Molecules and their Interaction Relevant to Biology

Major controls of de novo AMP synthesis include:

1. allosteric inhibition by GMP.
2. allosteric inhibition by AMP.
3. availability of PRPP.
4. stimulation by GTP.
TLS Online TPP Program

#Question id: 30108

#Unit 1. Molecules and their Interaction Relevant to Biology

Aspartate plays a role in all of the following EXCEPT:
TLS Online TPP Program

#Question id: 30109

#Unit 1. Molecules and their Interaction Relevant to Biology

Allopurinol is an inhibitor of xanthine oxidase. Administration of allopurinol to a patient with gout and normal HG-PRT levels would be expected to lead to all of the following EXCEPT:
TLS Online TPP Program

#Question id: 30110

#Unit 1. Molecules and their Interaction Relevant to Biology

The ribose phosphate group of purine nucleotide is taken from which compound?
TLS Online TPP Program

#Question id: 30111

#Unit 1. Molecules and their Interaction Relevant to Biology

What is the source of the C-2 during the de novo biosynthesis of pyrimidines?