Following statements are regarding to enzymatic processing of benzo(a)pyrene to a more potent mutagen and carcinogen.

A. Liver enzymes, particularly P-450 enzymes, modify benzo(a)pyrene in a series of reactions, producing 7,8-diol-9,10-epoxide, a highly potent mutagenic species that reacts with DNA primarily at the N2 atom of a guanine base.

B. The adduct, (+)-trans-anti-B(a)P-N2-dG, causes polymerase to insert an A rather than a C opposite the modified G base. Next time the DNA is replicated, a T will be inserted opposite the A, and the mutation will be complete.

C. Potent mutagen majorly causes conversion of guanine (G) to thymine (T) bases, a transition mutation.

D. When this potent mutagen applied to cultured bronchial epithelial cells, activated benzo(a)pyrene induces many mutations, including activating mutations at codons 175, 248, and 273 of the p53 gene.

Which of the following statements are correct?

#Question id: 4918

#Unit 8. Inheritance Biology

The two organelles responsible for cytoplasmic inheritance among eukaryotes are

#Question id: 4919

#Unit 8. Inheritance Biology

Genes for cytoplasmic male sterility in plants are generally located in

#Question id: 4920

#Unit 8. Inheritance Biology

In Neurospora, the mutant stp exhibits erratic stop-and start growth. When a female of stp strain is crossed with a normal strain acting as a male, all progeny individuals' showed stp mutant phenotype. However, the reciprocal cross resulted in all normal progeny, individuals. These results can be explained on the basis of

A. Uniparental gene contribution

B. Nuclear inheritance with concept of dominance

C. Sex link character

D. stp mutation may be located in chloroplast DNA

The most appropriate statement or combination of the above statements for explaining the experimental results is:

#Question id: 4921

#Unit 8. Inheritance Biology

Shell coiling in snail determine by genetic maternal effect. S for dextral and s for sinistral.  Following cross allowed between

Which of the following progeny not have SS genotype?

#Question id: 4922

#Unit 8. Inheritance Biology

Following statement is correct for Genetic maternal effect. 

A- Characteristics are determined by autosomal genes

B- Inherited according to Mendel’s principles

C- Phenotype of offspring determine by protein factor that is inherited via egg cytoplasm

#Question id: 4923

#Unit 8. Inheritance Biology

following statement given for Genetic maternal effect are correct?

A- Characteristics are determined by nuclear gene

B- Inherited according to Mendel’s principles

C- In F3 generation, segregation of Dominant trait and recessive trait in ratio of 3:1

D) No Segregation of Trait in F2 generation