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TLS Online TPP Program

#Question id: 1528

Mutation of p53 is described as a dominant-negative mutation. Which of the following statement is correct regarding to the mechanism by which this mutation causes the dominant-negative phenotype?

#Unit 4. Cell Communication and Cell Signaling

  1. Mutation of p53 is a dominant-negative mutation because the active protein is a dimer of identical subunits; the presence of even one defective subunit in the complex abrogates its function.

  2. Mutation of p53 is a dominant-negative mutation because the active protein is a pentamer of identical subunits; the presence of even one defective subunit in the complex abrogates its function.

  3. Mutation of p53 is a dominant-negative mutation because the active protein is a tetramer of identical subunits; the presence of even one defective subunit in the complex abrogates its function.

  4. Mutation of p53 is a dominant-negative mutation because the active protein is a heptamer of identical subunits; the presence of even one defective subunit in the complex abrogates its function.

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TLS Online TPP Program

#Question id: 2018

#Unit 4. Cell Communication and Cell Signaling

What aspect of the immune response would a patient who has a parasitic worm infection and another patient responding to an allergen such as ragweed pollen have in common?
TLS Online TPP Program

#Question id: 2019

#Unit 4. Cell Communication and Cell Signaling

Which of the following is not a component of an insectʹs defense against infection?
TLS Online TPP Program

#Question id: 2020

#Unit 4. Cell Communication and Cell Signaling

Which statement best describes the difference in responses of effector B cells (plasma cells) and cytotoxic T cells?
TLS Online TPP Program

#Question id: 2021

#Unit 4. Cell Communication and Cell Signaling

Which one of the following is not true for class 2 MHC protein?
TLS Online TPP Program

#Question id: 2022

#Unit 4. Cell Communication and Cell Signaling

Which one of the following is not true for class 1 MHC protein?
TLS Online TPP Program

#Question id: 2023

#Unit 4. Cell Communication and Cell Signaling

Which of the following is a pathway that would lead to the activation of cytotoxic T cells?