#Question id: 28510
#Unit 5. Developmental Biology
which of the folllowing in turn function as positively feedback during limb bud formation?
#Question id: 23088
#Unit 12. Applied Biology
#Question id: 5934
#General Aptitude
September 13 , 1992 was a Sunday . Then which of the following is true ?
#Question id: 19029
#Unit 9. Diversity of Life Forms
#Question id: 2986
#Unit 2. Cellular Organization
During ubiquitin-mediated protein degradation in various events of cell cycle, ubiquitin-protein ligases ubiquitinylate substrate proteins, marking them for degradation by proteasomes. Cyclins are degraded through the action of two different ubiquitin-protein ligases, SCF and the anaphase-promoting complex or cyclosome. Following statements are regarding to SCF and APC/C.
A. SCF controls the G1–S phase transition by degrading G1/S phase cyclins and, CDK inhibitory proteins.
B. APC/C degrades S phase and mitotic cyclins, thereby promoting the exit from mitosis.
C. SCF and APC/C are multi-subunit ubiquitin-protein ligases that belong to the RING finger family of ubiquitin protein ligases.
D. SCF and APC/C belong to the different ubiquitin-protein ligase family, their regulation is same.
E. SCF recognizes its substrates only when they are phosphorylated.
F. SCF and APC/C both recognizes its substrates only when they are phosphorylated.
Which of the following is incorrect?