TLS Online TPP Program

#Question id: 2490


Which of the following is true regarding the transport of cargo by cytoplasmic dynein?

#Unit 2. Cellular Organization
  1. Dynactin is the protein that links dynein to microtubules.

  2. Transport is toward the (+) end of the microtubules.

  3. GTP binds to the head region of dynein.

  4. LIS1 associates with the head region of dynein to facilitate transport.

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TLS Online TPP Program

#Question id: 41386

#Unit 11. Bioinformatics

Q. Consider the following statements about BLOSUM62 in MSA.
1.BLOSUM62 provides substitution scores for amino-acid pairs.
2.Identical amino acids always receive the same score regardless of their identity.
3.A substitution between different amino acids can receive a positive or negative score.
4. BLOSUM62 is a nucleotide substitution matrix.
Which statements are correct?

TLS Online TPP Program

#Question id: 41387

#Unit 11. Bioinformatics

Q. An MSA contains five protein sequences. How many residue pairs are considered per column when calculating the SP score?

TLS Online TPP Program

#Question id: 41388

#Unit 11. Bioinformatics

Q. Assertion:The SP score of an MSA is calculated by summing the scores of all possible residue pairs in each column.
Reason:For (n)sequences, the number of distinct sequence pairs per column is (n(n-1)/2).


TLS Online TPP Program

#Question id: 41389

#Unit 11. Bioinformatics

Q. Assertion:The SP score of an MSA is calculated by summing the scores of all possible residue pairs in each column.
Reason:For (n)sequences, the number of distinct sequence pairs per column is (n(n-1)/2).

TLS Online TPP Program

#Question id: 33665

#Unit 11. Bioinformatics

In genome data analysis, Hidden Markov Models are widely used for

TLS Online TPP Program

#Question id: 33723

#Unit 11. Bioinformatics

In RNA-seq data analysis, a gene is expressed at higher level in condition I with log2 fold-change of 8, as compared to condition II. What does it imply?