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TLS Online TPP Program

#Question id: 2551

Gaucher disease is the most common of lipid storage diseases in humans. It is caused by a deficiency of an enzyme necessary for the breakdown of lipids. This leads to the accumulation of fatty material in organs of the body including the spleen, liver, kidneys, lungs, brain, and bone marrow. Using your knowledge of the structure of eukaryotic cells, identify the statement below that best explains how internal membranes and the organelles of cells may be involved in Gaucher disease.

#Unit 2. Cellular Organization

  1. The mitochondria are most likely defective and do not produce adequate amounts of ATP needed for cellular energy.

  2. The rough endoplasmic reticulum contains too many ribosomes, which results in an overproduction of the enzyme involved in lipid breakdown.

  3. The lysosomes lack sufficient amounts of enzymes necessary for the metabolism of lipids.

  4. The Golgi apparatus produces vesicles with faulty membranes, which fail to be transported to the plasma membrane for secretion.

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TLS Online TPP Program

#Question id: 30696

#Unit 1. Molecules and their Interaction Relevant to Biology

In the pathways for the breakdown of GM1, globoside, and sphingomyelin to ceramide, the ratio of residue  Glc ,Gal, GalNAc, Neu5Ac changes with different compound

Which of the following is incorrectly paired
TLS Online TPP Program

#Question id: 30697

#Unit 1. Molecules and their Interaction Relevant to Biology

Which of the following is true regarding Plasmalogen and Platelet-activating factor

a. The head group of Plasmalogen – ethanolamine
b. The head group of Plasmalogen – choline
c. The head group of Platelet-activating factor – ethanolamine
d. The head group of Platelet-activating factor – choline
TLS Online TPP Program

#Question id: 31014

#Unit 4. Cell Communication and Cell Signaling

If the insulin concentration rises fivefold to 2.5 × 10−11 M, as it does after a meal, and the Kd for binding of insulin to its receptor on liver cells, 1.4 × 10−10 M (0.14 nM). What fraction of insulin receptors with bound insulin? 
TLS Online TPP Program

#Question id: 31015

#Unit 4. Cell Communication and Cell Signaling

A ligand binds two different receptors with a Kd value of 10−7 M for receptor 1 and a Kd value of 10−9 M for receptor 2. For which receptor does the ligand show the greater affinity?
TLS Online TPP Program

#Question id: 31016

#Unit 4. Cell Communication and Cell Signaling

Epinephrine binding to its receptor stimulates:
TLS Online TPP Program

#Question id: 31017

#Unit 4. Cell Communication and Cell Signaling

When the signaling molecules are synthesized and secreted by signaling cells, transported through the circulatory system and finally act on target cells distant from their site of synthesis, called as: