Following statements are regarding to mechanism of kinesin-1 movement.

A. Initially leading head tightly bound to the microtubule and not bound by any nucleotide, while the trailing head is weakly bound to the microtubule and has ADP bound.

B. Binding of ATP induces a conformational change causing the linker to swing forward and dock into the head. This motion swings the former trailing head to become the leading head.

C. Binding of ATP induces a conformational change causing the linker to swing forward and dock into the head. This motion swings the former leading head to become the trailing head.

D. When leading head releases ADP and coordinately the trailing head hydrolyzes ATP to ADP + Pi. Pi is released and the linker becomes undocked.

E. When trailing head releases ADP and coordinately the leading head hydrolyzes ATP to ADP + Pi. Pi is released and the linker becomes undocked.

Which of the following combination is correct?

#Question id: 11155

#Unit 9. Diversity of Life Forms

Nucleic acid sequences that undergo few changes over the course of evolutionary time are said to be conserved. Conserved sequences of nucleic acids

#Question id: 11156

#Unit 9. Diversity of Life Forms

Species that are not closely related and that do not share many anatomical similarities can still be placed together on the same phylogenetic tree by comparing their

#Question id: 11157

#Unit 9. Diversity of Life Forms

Typically, mutations that modify the active site of an enzyme are more likely to be harmful than mutations that affect other parts of the enzyme. A hypothetical enzyme consists of four domains (A—D), and the amino acid sequences of these four domains have been determined in five related species. Given the proportion of amino acid homologies among the five species at each of the four domains, which domain probably contains the active site?

#Question id: 11158

#Unit 9. Diversity of Life Forms

Which of these items does not necessarily exist in a simple linear relationship with the number of gene-duplication events when placed as the label on the vertical axis of the graph below?

#Question id: 11159

#Unit 9. Diversity of Life Forms

Which kind of DNA should provide the best molecular clock for gauging the evolutionary relatedness of several species whose common ancestor became extinct billions of years ago?

#Question id: 11160

#Unit 9. Diversity of Life Forms

A phylogenetic tree constructed using sequence differences in mitochondrial DNA would be most valid for discerning the evolutionary relatedness of