TLS Online TPP Program

#Question id: 2732


DNA is an important therapeutic target for the intercalating agent class of drugs. These drugs work by:

#Unit 2. Cellular Organization
  1. Occupying the space between base pairs forming a stable complex.

  2. Forming hydrogen bonds with active site amino acid residues.

  3. Promoting the unwinding of the DNA double helix.

  4. Preventing the formation of base pairs.

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TLS Online TPP Program

#Question id: 27079

#Unit 1. Molecules and their Interaction Relevant to Biology

The van der Waals interaction as a function of interatomic distance r, then which of the following equation is correct 

TLS Online TPP Program

#Question id: 27080

#Unit 1. Molecules and their Interaction Relevant to Biology

Choose the correct statement about Vander-wall interaction  
1. Van der Waals potential (Evdw) is the sum of all interactions over all atoms
2. Van der Waals potential (Evdw)  is calculated by
3. This type of interaction is often called a 6–12 interaction, or the Leonard Jones potential.
4. Van der Waals forces are extremely weak, especially when compared with other forces influencing protein conformation

TLS Online TPP Program

#Question id: 27081

#Unit 1. Molecules and their Interaction Relevant to Biology

Which of the following is correctly describing the A dihedral angle or torsion angle 

TLS Online TPP Program

#Question id: 27082

#Unit 1. Molecules and their Interaction Relevant to Biology

Choose the incorrect statement regarding β -turns

TLS Online TPP Program

#Question id: 27083

#Unit 1. Molecules and their Interaction Relevant to Biology

Which of the following is correctly describing the differences between β Turn type I & β Turn type II

(1) type I & II i + 1 values differ only in psi values 

(2) type I & II i + 1 values differ only in phi values 

(3) type I & II i + 2 values differ only in phi values 

(4) type I & II i + 2 values differ only in psi values

TLS Online TPP Program

#Question id: 27084

#Unit 1. Molecules and their Interaction Relevant to Biology

How many bonded atoms are required to constitute a dihedral (torsion) angle, such as phi or psi?