Hybridization between mature mRNA and DNA can identify introns in eukaryotic genes. When mature mRNA produced by the insulin gene is hybridized with denatured chromosomal DNA, which of the following will most likely be observed?

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#Question id: 861

#Unit 1. Structure and Function of Biomolecules

Alexander Varshavsky discovered, the half-lives of many cytoplasmic proteins vary with the identities of their N-terminal residues via the so-called N-end rule:-

A. Destabilizing N-terminal residues Asp, Arg, Leu, Lys, and Phe have half-lives of	i. Only 2 to 3 minutes,
B. Stabilizing N-terminal residues Ala, Gly, Met, Ser, Thr, and Val have half-lives of	ii. >10 hours in prokaryotes iii. >20 hours in eukaryotes.

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#Question id: 862

#Unit 1. Structure and Function of Biomolecules

Match the following

lysosomal protein degradation pathways	Found in
1. Nonselective	a-well-nourished cells	i-containing the pentapeptide Lys-Phe-Glu-Arg-Gln
2- Selective	b-starving cells

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#Question id: 863

#Unit 1. Structure and Function of Biomolecules

Ubiquitinated proteins are proteolytically degraded in an ATP-dependent process mediated by a large (∼2500 kD, 26S) multiprotein complex named the 26S proteasome;

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#Question id: 864

#Unit 1. Structure and Function of Biomolecules

Which one is not the appropriate function of Heat Shock Proteins;

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#Question id: 865

#Unit 1. Structure and Function of Biomolecules

In autophagy, the endoplasmic reticulum (ER) first gives rise to a cup-shaped, membranous cisterna called the______

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#Question id: 866

#Unit 1. Structure and Function of Biomolecules

Which of the following is known as Sanger’s reagent