Which of the following statements is INCORRECT regarding the assembly of DNA into higher-order chromatin structure?

I. Histone H1 is not part of the histone octamer, but binds to linker DNA and is responsible for higher-order chromatin structure.

II. The 30 nm fibers of a chromosome are attached to a/an RNA-protein scaffold that holds the fibers in large loops.

III. It is not possible for linear DNA to be supercoiled. Only circular DNA, which has no ends, can have regions of supercoiling.

IV. Core histones lacking their amino-terminal tails are capable of forming 30-nm fibers as they help to stabilize the 30-nm fiber in internucleosomal interactions.

TLS Online TPP Program

#Question id: 27093

#Unit 1. Molecules and their Interaction Relevant to Biology

Say a, b, c, d, e, f, g  are the amino acid forming αα motif / Coiled-coils then which of the condition must be followed to form perfect αα motif / Coiled-coil

(1) 'a' & 'd' are hydrophobic residues

(2) 'a' & 'd' are hydrophilic residues

(3) 'e' and 'g' are found to be charged amino acids

(4) 'e' and 'g' are found to be uncharged amino acids

TLS Online TPP Program

#Question id: 27094

#Unit 1. Molecules and their Interaction Relevant to Biology

Which of the following is incorrect regarding the βαβ Motif

TLS Online TPP Program

#Question id: 27095

#Unit 1. Molecules and their Interaction Relevant to Biology

Which of the following is correct regarding the Type I β turn positions  Ramachandran plot

TLS Online TPP Program

#Question id: 27096

#Unit 1. Molecules and their Interaction Relevant to Biology

Which of the following is incorrect regarding the Type II β turns

TLS Online TPP Program

#Question id: 27097

#Unit 1. Molecules and their Interaction Relevant to Biology

Which of the following is correct regarding the β turns

(1) In Type I β turn i+1 lies in RHH region while i+2 lies near BS region

(2) In Type II β turn i+1 lies in BS while i+2 lies in below LHH

(3) In Type I’ β i+1and i+2 in near LHH which virtually not allowed region for most of amino acid except Gly

(4) In Type II’ β i+2 lies at 00 psi and i+1 in lower right region both i+2 and   i+1  must be Gly

TLS Online TPP Program

#Question id: 27098

#Unit 1. Molecules and their Interaction Relevant to Biology

On what positions Beta turns are characterised