#Question id: 7245
#Unit 5. Developmental Biology
Gradients of Wnt are essential for normal regeneration of a head and a tail by planaria. Which one of the following statement is incorrect?
#Question id: 7246
#Unit 5. Developmental Biology
Treatment of Xenopus embryos with lithium dorsalizes the embryos by interfering with cell-cell signaling pathways. What, if anything, is the effect of lithium on hydra, and what might we infer about its mechanism of action?
#Question id: 7247
#Unit 5. Developmental Biology
Which statement correctly characterizes regeneration in the mammalian nervous system?
#Question id: 7248
#Unit 5. Developmental Biology
Planning of the Xenopus mesoderm along the dorso-ventral axis contains an antagonistic relationship between chordin and bmp-4. Is there an analogy here to dorso-ventral patterning in the Drosophila embryo?
#Question id: 7249
#Unit 5. Developmental Biology
Match the following proteins (column I) in nematodes with their functions
(column II).
Column
I |
Column
II |
A.
SKN-1 |
i.
specify the Anterior-Posterior axis |
B.
TBX-35 |
ii.
specify MS fates |
C.
MOM-2 and MOM-5 |
iii.
controls the fate of the EMS blastomere |
D.
PHA-4 |
iv.
activates mesodermal genes in the MS cell |
Which of the following is correct?
#Question id: 7250
#Unit 5. Developmental Biology
Following
statements are regarding to signals that regulate axis extension in chick
embryos.
A.
In the stage 10 chick embryo, Fgf8 inhibits expression of the retinoic acid
(RA) synthesizing enzyme Raldh2 in the presomitic mesoderm and the expression
of the RA receptor RARβ in the neural ectoderm, thus preventing RA from
triggering differentiation in the caudal-lateral epiblast cells and the
caudal-most paraxial mesoderm.
B.
Fgf8 inhibits Sonic hedgehog (Shh) expression in the neural tube floorplate,
controlling the onset of ventral patterning genes.
C.
FGF signaling is also required for expression of Delta1 in the medial portion
of the caudal-lateral epiblast cells and promotes expression of Wnt8c.
D.
Fgf8 decays in the caudal paraxial mesoderm, Wnt signaling, most likely
provided by Wnt8c, now acts to promote Raldh2 in the adjacent paraxial mesoderm.
RA produced by Raldh2 activity expresses Fgf8 and Wnt8c.
Which of the following statements are correct?