TLS Online TPP Program

#Question id: 2901


HOTAIR is a lncRNA whose gene is found in the HoxC cluster in humans, but it acts by regulating expression of the HoxD genes on another chromosome (in trans) by recruiting to that locus Polycomb Repressive Complex 2 (PCR2). Which of the following processes is incorrect regarding this regulation?

#Unit 2. Cellular Organization
  1. PRC2 adds trimethyl groups to lysine 9 of histone H3, a mark (H3K9me3) associated with repressed gene expression.

  2. HOTAIR also recruits a second complex that removes histone modifications typically associated with active genes.

  3. HOTAIR has also been found to be up-regulated in some cancers. Deleting the PRC2-binding domain of HOTAIR destroys its regulatory functions in both development and cancer.

  4. HOTAIR never found to be up-regulated in some cancers. Deleting the PRC2-binding domain of HOTAIR destroys its regulatory functions in both development and cancer.

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TLS Online TPP Program

#Question id: 4812

#Unit 8. Inheritance Biology

Two character X and Y ,both follow law of dominance due to 3:1 F2 phenotypic ratio monohybrid cross separately If carry out dihybrid selfing cross for heterozygous genotype for both character does not follow law of independence assortment in normal environmental condition due to?

TLS Online TPP Program

#Question id: 4813

#Unit 8. Inheritance Biology

You perform the three different two-factor crosses (Cross 1: XY and xy, Cross 2: YZ and yz, and Cross 3: XZ and xz). Assume all crosses are between diploid flies homozygous for the alleles of these genes. You observe 7% recombinants in the first cross, 20% recombinants in the second cross, and 13% recombinants in the third cross. if cross between XyZ and xYz leads to which of the followining recombinant with double cross over .

TLS Online TPP Program

#Question id: 4814

#Unit 8. Inheritance Biology

The frequency of recombinant gametes is half the frequency of crossing over between genes present on same chromosome is due to

TLS Online TPP Program

#Question id: 4815

#Unit 8. Inheritance Biology

The cross over percentage between linked genes J and M is 20%, J and L is 35%, J and N is 70%, L and K is 15%, M and N 50%. The sequence of genes on the chromosome is

TLS Online TPP Program

#Question id: 4816

#Unit 8. Inheritance Biology

A wild-type fruit fly heterozygous for gray body color and normal wings was mated with a black fly with vestigial wings to produced 1000 offspring. Recombination frequency between these genes for body color and wing type is 20 %. What number of offspring that is gray body colour and normal wing?

TLS Online TPP Program

#Question id: 4817

#Unit 8. Inheritance Biology

How many different gametes can be formed by an organism with genotype AaBbCCddEe, If a, b and c gene are completely link?