TLS Online TPP Program

#Question id: 5132


Upon secretion of wnt, When Wnt attaches to the Frizzled receptor on a responding cell, the cell secretes Notum, a hydrolase that associates with glypican and then cleaves off Wnt’s attached lipids in a process of deacylation or delipidation. This process:

#Unit 5. Developmental Biology
  1. reduces Wnt signaling because the lipids are essential for Wnt to bind to Frizzled

  2. Increases wnt signaling because lipids are not essential for wnt to bind to frizzled

  3. Firstly increases, later on reduces wnt signalling.

  4. Firstly reduces, later on increase wnt signaling

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TLS Online TPP Program

#Question id: 49

#Unit 1. Molecules and their Interaction Relevant to Biology

The equilibrium constant, Keq, for the following reaction is 2 × 105 M: If the measured cellular concentrations are [ATP] = 5 mM, [ADP] = 0.5 mM, and [Pi] = 5 mM, on the basis of the above information calculate the Keq in living cells?

TLS Online TPP Program

#Question id: 50

#Unit 1. Molecules and their Interaction Relevant to Biology

The enzyme fumarase catalyzes the reverse hydration of fumaric acid to l-malate, but it will not catalyze the hydration of maleic acid, the cis isomer of fumaric acid. This is an example of:

TLS Online TPP Program

#Question id: 51

#Unit 1. Molecules and their Interaction Relevant to Biology

 If the equilibrium constant, Keq, for the reaction ATP → ADP + Pi is 2.22 × 105 M, calculate the standard free-energy change, ΔG°, for the synthesis of ATP from ADP and Pi at 25 °C.

TLS Online TPP Program

#Question id: 52

#Unit 1. Molecules and their Interaction Relevant to Biology

Choose the incorrect option regarding Isomerism.

TLS Online TPP Program

#Question id: 53

#Unit 1. Molecules and their Interaction Relevant to Biology

Calculate the number of times the DNA of a modern E. coli cell has been copied accurately since its earliest bacterial precursor cell arose about 3.5 billion years ago. Assume for simplicity that over this time period, E. coli has undergone, on average, one cell division every 12 hours (this is an overestimate for modern bacteria, but probably an underestimate for ancient bacteria).

TLS Online TPP Program

#Question id: 54

#Unit 1. Molecules and their Interaction Relevant to Biology

About 25 of the 92 natural elements are known to be essential to life. Which 4 of these 25 elements make up approximately 96% of living matter?