Penicillin is an antibiotic that inhibits enzymes from catalyzing the synthesis of peptidoglycan, so which prokaryotes should be most vulnerable to inhibition by penicillin?

#Question id: 81

#Unit 1. Molecules and their Interaction Relevant to Biology

The Fischer projections of linear D-glucose and D-galactose are shown below. These two molecules are

#Question id: 2805

#Unit 2. Cellular Organization

There is a roughly inverse correlation between organism complexity and gene density

#Question id: 1835

#Unit 4. Cell Communication and Cell Signaling

The HIV nef protein affects antigen presentation by:

#Question id: 1028

#Unit 4. Cell Communication and Cell Signaling

The capsule

#Question id: 10308

#Unit 1. Molecules and their Interaction Relevant to Biology

Oxidative decarboxylation of pyruvate to acetyl-CoA by the PDH complex, how the pyruvate dehydrogenase complex carries out the five consecutive reactions in the decarboxylation and dehydrogenation of pyruvate?

 A) Pyruvate reacts with the bound thiamine pyrophosphate (TPP) of pyruvate dehydrogenase, undergoing decarboxylation to the hydroxyethyl derivative

 B) A transesterification in which the —SH group of CoA replaces the —SH group of E2 to yield acetyl-CoA and the fully reduced (dithiol) form of the lipoyl group

 C) The reduced FADH2 of E3 transfers a hydride ion to NAD1 , forming NADH, the enzyme complex is now ready for another catalytic cycle

 D) The transfer of two electrons and the acetyl group from TPP to the oxidized form of the lipoyllysyl group of the core enzyme, dihydrolipoyl transacetylase, to form the acetyl thioester of the reduced lipoyl group

 E) Dihydrolipoyl dehydrogenase promotes transfer of two hydrogen atoms from the reduced lipoyl groups of E2 to the FAD prosthetic group of E3 , restoring the oxidized form of the lipoyllysyl group of E2

 Find out the correct sequence of action of this complex enzyme?