Nucleosome DNA wraps around the histone protein 1.65 times, so create a writhe of –1.65 and so DLk should be -1.65. But when the change in linking number associated with each nucleosome was measured, the number was lower than this, approximately –1.2 for each nucleosome added. This discrepancy is referred to as the 

TLS Online TPP Program

#Question id: 4494

#Unit 3. Fundamental Processes

Propagation of certain repressing histone modifications over stretches of chromatin lies at the heart of a phenomenon is known,

TLS Online TPP Program

#Question id: 4495

#Unit 3. Fundamental Processes

_ elements can block this spreading, protect genes from both indiscriminate activation and repression.

TLS Online TPP Program

#Question id: 4496

#Unit 3. Fundamental Processes

Facilitates chromatin transcription was identified in human cell extracts, this factor makes transcription on chromatin templates much more efficient, choose correct statements;

TLS Online TPP Program

#Question id: 4497

#Unit 3. Fundamental Processes

Elongation, termination of transcription, and RNA processing are interconnected, presumably to ensure their proper coordination,

Elongation factors
I.    hSPT5	To recruit the 5’ -capping enzyme to the CTD tail of polymerase
II.   TAT-SF1	To recruits components of the splicing machinery to polymerase with a Ser-2 phosphorylated tail

TLS Online TPP Program

#Question id: 4498

#Unit 3. Fundamental Processes

Which enzyme is used in this particular mechanism;

TLS Online TPP Program

#Question id: 4499

#Unit 3. Fundamental Processes

The final RNA processing event, polyadenylation of the 3’end of the mRNA, is intimately linked with the termination of transcription. Just as with capping and splicing, the polymerase CTD tail is involved in recruiting some of the enzymes necessary for polyadenylation,