MAR fragments are usually

TLS Online TPP Program

#Question id: 15338

#Unit 4. Cell Communication and Cell Signaling

Which cell generated on the receipt of SCF/c-Kit signaling lose the capacity for extensive self-renewal, but retain the potential to differentiate into several different hematopoietic lineages and also transiently express the molecule CD34?

TLS Online TPP Program

#Question id: 15339

#Unit 4. Cell Communication and Cell Signaling

HSCs begin their life in close contact with osteoblasts located close to the lining of the endosteal cavity. Once differentiated to the pre-pro-B-cell stage, the developing B cells require Which type of signals from the chemokine, which is secreted by a specialized set of stromal cells?

TLS Online TPP Program

#Question id: 15340

#Unit 4. Cell Communication and Cell Signaling

Serrogate light chain formation takes place in 

TLS Online TPP Program

#Question id: 15341

#Unit 4. Cell Communication and Cell Signaling

Formation of pre B-cell  describing__

A. Surrogate light chain formation 

B. On these surface present IgM

C. Heavy chain had been formed

D. DJ H chain recombination

TLS Online TPP Program

#Question id: 15342

#Unit 4. Cell Communication and Cell Signaling

The heavy chain is then expressed on the cell surface in combination with the surrogate light chain, which is made up of_______________, together they form the pre-B-cell receptor,

TLS Online TPP Program

#Question id: 15360

#Unit 4. Cell Communication and Cell Signaling

The cytochrome P450 constitute a superfamily of heme-containing enzymes that occur in nearly all living organisms, from bacteria to mammals, These monooxygenases, which in animals are embedded in the endoplasmic reticulum membrane, catalyze reactions of the sort

                  RH + O₂ + 2 H⁺ + 2e⁻ → ROH + H₂O 

The electrons (e−) are supplied by NADPH, which passes them to cytochrome P450’s heme prosthetic group via the intermediacy of the enzyme NADPH P450 reductase. Here RH represents a wide variety of usually lipophilic compounds for which the different cytochromes P450 are specific. They include

a. polycyclic aromatic hydrocarbons 

b. polycyclic biphenyls

c. frequently carcinogenic compounds that are present in tobacco smoke, broiled meats, and other pyrolysis products

d. which were widely used in electrical insulators and as plasticizers and are also carcinogenic.