TLS Online TPP Program

#Question id: 2947


You perform an experiment where you prevent Cdc20 from binding to APC  in a cell line that usually completes the cell cycle in 60 minutes. Your experiment prevents Cdc20 from binding to APC for 120 minutes, and then you fix and stain the DNA, securin, separase and cohesin proteins. Which of the following would NOT be found in the observed cell?

#Unit 2. Cellular Organization
  1. The cell would contain condensed chromosomes aligned at the metaphase plate.

  2. Cohesins will be localized around the sister chromatids.

  3.  Securin would be bound to separase (appear to co-localize).

  4. The DNA will be decondensed because the cell is in interphase.