TLS Online TPP Program

#Question id: 3952


What kind of molecules must pass between the nucleus and the cytoplasm?

#Unit 3. Fundamental Processes
  1. DNA

  2. protein

  3. lipids

  4. carbohydrates

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TLS Online TPP Program

#Question id: 26882

#Unit 10. Ecological Principles

increasing distance of the island from the mainland, then what will caused?

TLS Online TPP Program

#Question id: 15737

#Unit 12. Applied Biology

The basic event of development in higher organisms is

TLS Online TPP Program

#Question id: 1514

#Unit 4. Cell Communication and Cell Signaling

Following statements are regarding to multiple signaling pathways in vertebrate cells that regulate outer mitochondrial membrane permeability and apoptosis.

A. In healthy cells, the anti-apoptotic protein Bcl-2, or its homolog Bcl-xL, binds to Bak or Bax pro-apoptotic proteins, blocking the ability of Bak or Bax to oligomerize and form pores in the outer mitochondrial membrane.

B. The presence of specific trophic factors (e.g., NGF) leads to activation of their cognate receptor tyrosine kinases (e.g., TrkA) and inactivation of the PI-3 kinase–PKB (protein kinase B) pathway.

C. PKB phosphorylates Bad, and phosphorylated Bad forms a complex with a cytosolic 14-3-3 protein. This sequestered Bad is unable to bind to Bcl-2.

D. In the absence of trophic factors, nonphosphorylated Bad binds to Bcl-2, releasing Bax and Bak and allowing them to form oligomeric membrane pores and holes.

E. DNA damage or ultraviolet irradiation leads to induction of synthesis of the BH3-only Puma protein. Puma binds to Bak and Bax as well as to Bcl-2, allowing Bak and Bax to form oligomeric pores.

F. Removal of a cell from its substratum disrupts integrin signaling, leading to release of the BH3-only Bim protein from the cytoskeleton. Bim also binds to Bak and Bax to promote pore formation.

Which of the following is incorrect?

TLS Online TPP Program

#Question id: 18737

#Unit 13. Methods in Biology

RNase S1 method and homopolymer tailing method generates blunt ended cDNA molecules. Which of the following can be used for attaching them to vector?

TLS Online TPP Program

#Question id: 28064

#Unit 1. Molecules and their Interaction Relevant to Biology

Which of the following Techniques can be used to for Measuring Stability of protein    
a. DSC (calorimetry) 
b. Urea gradient gels 
c. FRET
d. EPR
Which of the following is correct