Regulating iron levels in the human body is critical. Many proteins use iron as a cofactor, including the oxygen transport proteins hemoglobin and myoglobin. Consistent with the important role of iron in oxygen transport and energy production, a shortage of iron in the human body (called anemia) results in an overall feeling of weakness. On the other hand, excess iron is toxic to cells and can contribute to liver damage, heart failure, and diabetes. The iron-binding protein Ferritin is the major regulator of iron levels in the human body. Which of the following are INCORRECT regarding ferritin?

A. Ferritin translation is regulated by iron-binding proteins called iron regulatory proteins

B. The levels of transferrin, transferrin receptor, are also crucial to cellular iron homeostasis

C. Aconitase regulates synthesis of these three proteins is regulated in response to iron availability

D. apoaconitase, is actually IRE that has ability to bind to specific sequences in the mRNAs for the transferrin receptor and ferritin, thus regulating protein synthesis at the translational level.

E. IRE binding to mRNA increases synthesis of ferritin many folds.

#Question id: 4868

#Unit 8. Inheritance Biology

 A mouse cross C/c . D/d X c/c . d/d is made, and in the progeny there are

45% C/c . d/d, 45% c/c . D/d,

5% c/c . d/d, 5% C/c . D/d

What are distance between C and D gene?

#Question id: 4869

#Unit 8. Inheritance Biology

In the plant Arabidopsis, the loci for pod length (L, long; l, short) and fruit hairs (H, hairy; h, smooth) are linked 16 map units apart on the same chromosome. The following crosses were made:

(i) L H/L H X l h/l h = F1

(ii) L h/L h X l H/l H = F1

If the F1’s from (i) and (ii) are crossed, what proportion of the progeny are expected to l h/l h?

#Question id: 4870

#Unit 8. Inheritance Biology

Following gene order is for three points. If Genotype +y +ct +v produced actual number of double cross over gamete is 10 out of total 1000. What is interference value?

#Question id: 4871

#Unit 8. Inheritance Biology

In a testcross of an individual heterozygous for each of three linked genes, the most frequent classes of progeny were A B c/a b c and a b C/a b c, and the least frequent classes were A B C/a b c and a b c/a b c. what is the order of the genes?

#Question id: 4872

#Unit 8. Inheritance Biology

F1 heterozygous females are test-crossed with males and produced 1800 progeny The interference between these genes is 0.4. What number is of observe double cross over? 

#Question id: 4873

#Unit 8. Inheritance Biology

Six bands in a salivary gland chromosome of Drosophila are shown in the following figure, along with the extent of five deletions (Del 1 to Del 5)