Which of the following statements correctly describes a characteristic of tumor-suppressor gene?

TLS Online TPP Program

#Question id: 28928

#Unit 4. Cell Communication and Cell Signaling

In the cytosolic destruction complex, Ci becomes phosphorylated in a series of steps catalyzed by kinases which is?

TLS Online TPP Program

#Question id: 28929

#Unit 4. Cell Communication and Cell Signaling

In the cytosolic destruction complex, Ci becomes phosphorylated and is proteolytically cleaved by the ubiquitin-proteasome pathway, generating an N-terminal fragment Ci75, which functions as___

TLS Online TPP Program

#Question id: 28930

#Unit 4. Cell Communication and Cell Signaling

Hedgehog (Hh) presence causes__ 

a) binds to Smo, causing Smo to be endocytosed from the cell surface and degraded

b) binds to Ptc, causing Ptc to be endocytosed from the cell surface and degraded

c) degraded Ptc and relieving the inhibition of Smo

d) degraded Smo and relieving the inhibition of Ptc

TLS Online TPP Program

#Question id: 28931

#Unit 4. Cell Communication and Cell Signaling

Which of the following activity dissociates Fu-Cos2-Ci complex?

TLS Online TPP Program

#Question id: 31014

#Unit 4. Cell Communication and Cell Signaling

If the insulin concentration rises fivefold to 2.5 × 10⁻¹¹ M, as it does after a meal, and the Kd for binding of insulin to its receptor on liver cells, 1.4 × 10⁻¹⁰ M (0.14 nM). What fraction of insulin receptors with bound insulin? 

TLS Online TPP Program

#Question id: 31015

#Unit 4. Cell Communication and Cell Signaling

A ligand binds two different receptors with a Kd value of 10⁻⁷ M for receptor 1 and a Kd value of 10⁻⁹ M for receptor 2. For which receptor does the ligand show the greater affinity?