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#Question id: 4350


Portions of the DNA sequences of normal and mutant b-globin genes are shown. The most plausible explanation for why the indicated mutation (changing an A to a G) results in the disease b-thalassemia is that the mutation

#Unit 3. Fundamental Processes
  1. changes the amino acid specified by the codon of which the altered base is part

  2. generates a recognition site for a restriction enzyme, so the gene is cut in two

  3. creates a new splice site, so that a portion of the intron is not removed

  4. results in an increase in the transcription of the b-globin gene

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#Question id: 5751

#Unit 8. Inheritance Biology

A biochemical mutant that must be supplied with a particular nutrient for growth would be described as a(n)

TLS Online TPP Program

#Question id: 5752

#Unit 8. Inheritance Biology

base change that changes a codon for an amino acid to a stop codon

TLS Online TPP Program

#Question id: 5753

#Unit 8. Inheritance Biology

A bacterial histidine mutant was plated on minimal medium and a single colony grew. You decide to sequence the histidine biosynthetic gene of the revertant and discover that the original mutation is still present.  This colony must have been able grow due to a

TLS Online TPP Program

#Question id: 5754

#Unit 8. Inheritance Biology

A cell is exposed to EMS (a mutagen that causes guanine to mispair with thymine) and allowed to undergo a few rounds of DNA replication.  The mutational event caused by this mutagen will be

TLS Online TPP Program

#Question id: 5755

#Unit 8. Inheritance Biology

A researcher studying bacterial toxin predicts that a lysine within the toxin is important for binding it’s target cell.  She used site-directed mutagenesis to change a codon for lysine (AAA) to one for asparagine (AAU).  However, the mutant toxin still binds to its target cell just as well as the wild-type toxin bound and appears to have no other changes. This type of mutation is probably

TLS Online TPP Program

#Question id: 5756

#Unit 8. Inheritance Biology

Type of mutation caused by an addition or deletion of a base in a polypeptide-encoding part of a gene