TLS Online TPP Program

#Question id: 4445


The active site, which is made up of RPB1 and RPB2, from both these subunits, is found at the base of the pincers within a region called the “active center cleft” . The active site works according to the two-metal ion catalytic mechanism for nucleotide addition proposed for all types of polymerase;

#Unit 3. Fundamental Processes
  1. Mg (2+)

  2. Ca (2+)

  3. Na+

  4. Both A and B