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TLS Online TPP Program

#Question id: 15007

You set up a cross between true breeding wild type male fruit flies and true breeding female flies with a yellow body color. You notice in the F1 generation that half the flies, specifically all the males, have yellow body color while the females are wild type (gray). Which of the following explanations is the most likely?

#Unit 8. Inheritance Biology
  1. Some of your females had already mated with yellow males before you collected them.
  2. Some of your parental flies must have had a new mutation in their germ cells.
  3. The mutation which causes yellow body color is on the X chromosome.
  4. The mutation which causes yellow body color is on the Y chromosome.
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TLS Online TPP Program

#Question id: 12905

#Unit 13. Methods in Biology

Some gene/protein is used to identify the Disorder in humans Match them correctly:

1. Tyrosine Kinase(TK)i. Atherosclerosis
2. HIV transactivatorii. Hypertension
3. Angiotensinogeniii. Kaposis Sarcoma
4. CET proteiniv. Cardiac Hypertrophy
TLS Online TPP Program

#Question id: 12906

#Unit 13. Methods in Biology

An alternative method labeling strategy used in karyotyping and gene localisation is _______
TLS Online TPP Program

#Question id: 12907

#Unit 13. Methods in Biology

The binding of a regulatory protein or transcription factor to a specific DNA site results in a complex which may be analyzed by the technique termed as _____
TLS Online TPP Program

#Question id: 12908

#Unit 13. Methods in Biology

Which statement is incorrect about CRISPR?
TLS Online TPP Program

#Question id: 12909

#Unit 13. Methods in Biology

According to the diagram, arrange the steps in correct order: 


1. DNA is then digested by the Cas9 nuclease at specific points on both DNA strands. 
2. Homologous recombination to repair the break and incorporate the new DNA sequence then follows. 
3.The nuclease Cas9 is targeted to DNA by a guide RNA consisting of a specific 20 nucleotide spacer/targeting sequence (crRNA).
 4. That identifies the DNA to be modified, linked to a trans-activating (tracrRNA) sequence necessary for the recruitment and stability of Cas9 nuclease.
TLS Online TPP Program

#Question id: 12910

#Unit 13. Methods in Biology

Match the following:

A. RNA analysisi. Sexing or cell mutation sitesa. Expressed Sequence tag
B. Forensic scienceii. mRNA analysisb. Analysis of DNA from blood
C. Gene discoveryiii. DNA profilingc. Active latent viral infections
D. Single-cell analysisiv. RT–PCRd. Sex determination of unborn