#Question id: 19095
#Unit 4. Cell Communication and Cell Signaling
#Question id: 4110
#Unit 3. Fundamental Processes
Tay-Sachs disease belongs to the family of lysosomal storage diseases; it is an autosomal recessive neurodegenerative disorder caused by deficiency of the lysosomal enzyme hexosaminidase. The inability to degrade sphingolipids results in the deposition of these lipids in the cells that causes severe mental retardation and death in childhood. The most common mutation in Tay-Sachs disease patients is a 4-base pair insertion in exon 11 of the 14 exons of the hexosaminidase gene. What could be the most likely consequence of this mutation?
#Question id: 3299
#Unit 11. Evolution and Behavior
There are four alleles, A1, A2, A3 and A4 in equal abundance in frequency. Hardy-Weinberg equilibrium frequencies of the total heterozygote would be
#Question id: 7589
#General Aptitude
#Question id: 16962
#Unit 11. Evolution and Behavior