Elongation, termination of transcription, and RNA processing are interconnected, presumably to ensure their proper coordination,

Elongation factors
I.    hSPT5	To recruit the 5’ -capping enzyme to the CTD tail of polymerase
II.   TAT-SF1	To recruits components of the splicing machinery to polymerase with a Ser-2 phosphorylated tail

TLS Online TPP Program

#Question id: 15522

#Unit 4. Cell Communication and Cell Signaling

Double negative selection do not apply on which type of T-cells?

TLS Online TPP Program

#Question id: 15523

#Unit 4. Cell Communication and Cell Signaling

The appearance of ϒδ thymocytes and αβ thymocytes during mouse fetal development. Fetal animals generate

a) more αβ T-cells than ϒδ T-cells

b) the proportion of ϒδ T-cells generated drops off dramatically after birth

c) the proportion of αβ T-cells generated drops off dramatically after birth

d) more ϒδ T-cells than αβ T cells

TLS Online TPP Program

#Question id: 15524

#Unit 4. Cell Communication and Cell Signaling

The bulk of DP thymocyte death (~95%) occurs among thymocytes that fail positive selection because 

TLS Online TPP Program

#Question id: 15525

#Unit 4. Cell Communication and Cell Signaling

In the instructive model, TCR/CD4 and TCR/CD8 coengagement generates unique signals, if a thymocyte randomly generated a TCR with an affinity for MHC Class I. which thymocyte would bind with MHC class I?

TLS Online TPP Program

#Question id: 15526

#Unit 4. Cell Communication and Cell Signaling

If a thymocyte randomly generated a TCR with an affinity for MHC Class I, the TCR and CD8 would bind MHC Class I together, and generate a signal that specifically initiated a program that is 

a) silenced CD8 expression

b) silenced CD4 expression

c) induced expression of genes specific for helper T-cell lineage function

d) induced expression of genes specific for cytotoxic T-cell lineage function

TLS Online TPP Program

#Question id: 15527

#Unit 4. Cell Communication and Cell Signaling

CD4 and CD8 T cells leave the thymus and enter the circulation as resting cells in which stage of the cell cycle?