Promoters for Pol II typically have a TATA box and Inr sequence, as well as multiple binding sites for transcription activators. The latter sites, sometimes located hundreds or thousands of base pairs away from the TATA box, are called

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#Question id: 12494

#Unit 8. Inheritance Biology

Hunter syndrome is a rare form of mucopolysacchararidosis that differs from all other forms in that it shows X-linked recessive inheritance. A woman with two affected brothers is referred for genetic counselling. Which of the following is correct?

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#Question id: 12495

#Unit 8. Inheritance Biology

Haemophilia A is a severe coagulation disorder that shows X-linked recessive inheritance. Red-green colour blindness also shows X-linked recessive inheritance. A man with both haemophilia A and colour blindness is referred for genetic counseling. Assume that his partner is not a carrier of either of these conditions. Which of the following is correct?

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#Question id: 12496

#Unit 8. Inheritance Biology

A woman who has two brothers and a maternal uncle (her mother's brother) with non-specific X-linked mental retardation is referred for genetic counselling. There are no diagnostic tests available to help determine whether or not she is a carrier. Which of the following is correct?

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#Question id: 12497

#Unit 8. Inheritance Biology

In this pedigree A and B represent alleles at a marker locus closely linked to the disease locus. Affected individuals are shown as shaded. The disease status in III 1 is unknown. Which of the following is correct?

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#Question id: 12498

#Unit 8. Inheritance Biology

In this pedigree II 1 is affected with an autosomal recessive disorder. The disease status for II 2 and II 3 is unknown. A and B represent alleles at a locus which is tightly linked to the disease locus with recombination fraction of 0. On the basis of the linked marker genotypes II 2 can be told that: 

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#Question id: 12499

#Unit 8. Inheritance Biology

On the basis of the linked marker genotypes II 3 can be told that: