Practice Questions

TLS Online TPP Program

#Question id: 4952

Several scientific laboratories across the globe are involved in research concerning the origin of life on Earth. Which of these questions is currently the most problematic and would have the greatest impact on our understanding if we were able to answer it?

#Unit 11. Evolution and Behavior

How can amino acids, simple sugars, and nucleotides be synthesized abiotically?
How can RNA molecules catalyze reactions?
How did RNA sequences come to carry the code for amino acid sequences?
How could polymers involving lipids and/or proteins form membranes in aqueous environments?

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TLS Online TPP Program

#Question id: 33899

#Unit 2. Cellular Organization

A. In E.coli, a natural closed DNA that is negatively supercoiled.

B. The intercalation of ethidium bromide first removes the negative supercoils and then introduces positive supercoils.

TLS Online TPP Program

#Question id: 33900

#Unit 2. Cellular Organization

A. Bacterial genome have many independent chromosomal domains

B. Bacterial genome is circular and have many intertangled domains

C. Each domain consists of 40 kilobases (k2. of DNA

D. The existence of separate domains donot permit different degrees of supercoiling to be maintained in different regions of the genome.

Find true and false

TLS Online TPP Program

#Question id: 33904

#Unit 2. Cellular Organization

A. The bacterial nucleoid is 80% DNA by mass.

B. Bacteria have similar morphological features as of eukaryotic chromosomes,

C. Bacterial genomes are organized into definite substructures within the cell.

D. Bacterial Protein HU is a dimer that condenses DNA, possibly wrapping it into a beadlike structure.

Find true and false

TLS Online TPP Program

#Question id: 33905

#Unit 2. Cellular Organization

E. coli DNA in vivo corresponds to an average density of 1 negative superhelical turn/200 bp it means it has

TLS Online TPP Program

#Question id: 33906

#Unit 2. Cellular Organization

Which is correct combination of statements

A. Bacterial genome has independent sets of domains and each domain consists of a loop of DNA.

B. Presence of domain in genome can be analyzed by EtBR intercalation and DNase treatment

C. Early data suggested that each domain consists of 10kb-40 kb of DNA

TLS Online TPP Program

#Question id: 33907

#Unit 2. Cellular Organization

A circular DNA molecule with 580,070 bp. Calculate the molecular weight and contour length (when relaxed) of this molecule. What is Lko for the Mycoplasma chromosome? If σ=- 0.06, what is Lk?