TLS Online TPP Program

#Question id: 532


In glycolysis, fructose 1,6-bisphosphate is converted to two products with a standard free-energy change (DG'°) of 23.8 kJ/mol.  Under what conditions (encountered in a normal cell) will the free-energy change (DG) be negative, enabling the reaction to proceed to the right?

#Unit 1. Molecules and their Interaction Relevant to Biology
  1. If the concentrations of the two products are high relative to that of fructose 1,6-bisphosphate.

  2. The reaction will not go to the right spontaneously under any conditions because the DG'° is positive.

  3. Under standard conditions, enough energy is released to drive the reaction to the right.

  4. When there is a high concentration of fructose 1,6-bisphosphate relative to the concentration of products.

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TLS Online TPP Program

#Question id: 4022

#Unit 3. Fundamental Processes

You are studying the effects of α-amanitin, a poisonous cyclic octapeptide, on eukaryotic cells and have noticed that following treatment, there is no miRNA transcription. Based on this evidence you conclude that α-amanitin must be inhibiting:

TLS Online TPP Program

#Question id: 4023

#Unit 3. Fundamental Processes

Which of the following is a fundamental difference between gene regulation in bacteria compared with eukaryotes?

TLS Online TPP Program

#Question id: 4024

#Unit 3. Fundamental Processes

All of the following statements about the essential carboxy terminal domain (CTD) of RNA polymerase are true except:

TLS Online TPP Program

#Question id: 4025

#Unit 3. Fundamental Processes

You have identified a transcription factor and hypothesize that it binds to the promoter region of a gene that encodes a protein that causes cells to stop dividing. In order to test the interaction between the transcription factor and the DNA you will need to do a specific assay. Which one of the following would you use to test your hypothesis?

TLS Online TPP Program

#Question id: 4026

#Unit 3. Fundamental Processes

The human genome encodes transcription factors that contain an acidic activation domain that is phosphorylated in response to increased levels of the second messenger cAMP. Which one of the following contains one of these activation domains?

TLS Online TPP Program

#Question id: 4027

#Unit 3. Fundamental Processes

Enhancers are considered transcription-control elements that regulate the expression of eukaryotic genes. Which one of the following is true regarding these elements?