#Question id: 5814
#Unit 8. Inheritance Biology
A bacterial cell experiences a mutation as a result of exposure to nitrogen mustard and then divides several times to produce a total of eight cells. How many of the resulting cells would you expect to contain the mutation?
#Question id: 14818
#Unit 4. Cell Communication and Cell Signaling
#Question id: 10863
#Unit 10. Ecological Principles
According to the ____________ principle, two species with identical requirements for existence cannot coexist indefinitely
#Question id: 7049
#Unit 5. Developmental Biology
Invaginating cells during amphibian gastrulation, in which the main body of each cell is displaced toward the inside of the embryo while maintaining contact with the outside surface by way of a slender neck-
#Question id: 1364
#Unit 4. Cell Communication and Cell Signaling
In mice engineered to overexpress the syndecan-1 gene in the hypothalamic region of the brain and other tissues, normal control of feeding by antisatiety peptides is disrupted, and the animals overeat and become obese. Other studies have shown that syndecan-3 may also be involved in the regulation of feeding behavior. Given the following information, which of these outcomes might you expect in experimentally manipulated mice?
I. Hypothalmic expression of syndecan-3 is increased by fasting.
II. Syndecan-3 knockout mice are resistant to diet-induced obesity.
III. Heparinase can cleave syndecan-3 to release heparin sulfate GAG chains that may suppress the activity of antisatiety peptides and feeding behavior.
Following statements are:
A. Overexpression of heparinase in mice with normal levels of syndecan-3 would result in resistance to diet-induced obesity.
B. In mice with normal levels of syndecan-3, fasting followed by free access to a high-fat diet would lead to resistance to diet-induced obesity.
C. Lack of heparinase in mice with normal levels of syndecan-3 would result in animals that overeat and become obese.
D. Overexpression of heparinase in syndecan-3 knockout mice would reverse the resistance to diet-induced obesity.
Which of the following combination is correct?