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TLS Online TPP Program
#Question id: 33985
#Unit 2. Cellular Organization
To analyze existing MARs that are bound to the matrix in vivo, what is correct order of method
A. Chromosomal loops decondensed by extracting the chromatin proteins.
B. Removal of the DNA loops by treatment with restriction nucleases
C. Amplification of MAR and sequencing
TLS Online TPP Program
#Question id: 33986
#Unit 2. Cellular Organization
What is the relationship between the chromosome scaffold of dividing cells and the matrix of interphase cells
A. The same DNA fragments that are found within the nuclear matrix in vivo can be retrieved from the metaphase scaffold
B. Fragments containing MAR sequences can bind to a metaphase scaffold; it is likely that DNA contains a single type of attachment site.
C. In interphase cells the attachment site is connected to the nuclear matrix, whereas in mitotic cells it is connected to the chromosome scaffold.
TLS Online TPP Program
#Question id: 34102
#Unit 2. Cellular Organization
The CenH3 nucleosomes form the chromatin foundation for recruitment and assembly for
TLS Online TPP Program
#Question id: 34103
#Unit 2. Cellular Organization
A. A CEN fragment derived from one chromosome can replace the centromere of another chromosome with no apparent consequence.
B. CEN are used simply to attach the chromosome to the spindle, and play no role in distinguishing one chromosome from another.
TLS Online TPP Program
#Question id: 34104
#Unit 2. Cellular Organization
The Centromeric DNA sequence that binds to Cse4
TLS Online TPP Program
#Question id: 34105
#Unit 2. Cellular Organization
A. The histone H3 variant Cse4 is incorporated in the centromeric nucleosome.
B. The CBF3 protein complex that binds to CDE-III is essential for centromeric function.
C. The proteins that bind CEN serve as an assembly platform for the kinetochore and provide the connection to microtubules.
Find true and false