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TLS Online TPP Program

#Question id: 28478

 Select the correct statements about these transcriptional factors-sox2, oct4 and nanog ?
a) these transcriptional factors activating those genes required to maintain totipotency in embryonic stem cells
b) these transcriptional factors activating those genes required to maintain pluripotency in embryonic stem cells
c) these transcriptional factors repressing those genes whose products would lead to differentiation

#Unit 5. Developmental Biology
  1.  a and c
  2. b and c
  3. Only b
  4. Only c
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TLS Online TPP Program

#Question id: 30084

#Unit 2. Cellular Organization

Drosophila is considered a model system because it is quite easy to create transgenic lines harboring a variety of different genes. As a Drosophila geneticist, which one of the following is a DNA transposon that you would exploit to create a transgenic line?
TLS Online TPP Program

#Question id: 18981

#Unit 13. Methods in Biology

The pL promoter is controlled by the cl repressor protein of bacteriophage A. In practice, a temperature-sensitive mutant of the cl repressor, cl857, is generally used to regulate pL-directed transcription. Cells carrying the temperature-sensitive cl repressor are first grown at 30°C, and 42°C
TLS Online TPP Program

#Question id: 20969

#Unit 12. Applied Biology

Which of the following is the process of choosing parent organisms for the characteristics that is wanted in their offspring?
TLS Online TPP Program

#Question id: 792

#Unit 1. Molecules and their Interaction Relevant to Biology

Which arm of the tRNA can act as a structural recognition feature?
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#Question id: 889

#Unit 1. Molecules and their Interaction Relevant to Biology

The cis and trans GroEL rings undergo conformational changes in a reciprocating fashion, with events in one ring influencing events in the other ring. The entire GroEL/ES chaperonin complex functions as follows;

a) One GroEL ring that has bound 7 ATP also binds an improperly folded substrate protein, which associates with hydrophobic patches that line the inner wall of the GroEL chamber

b) The GroES cap then binds to the GroEL ring like a lid on a pot, inducing a conformational change in the resulting cis ring

c) Within ~10 s the cis ring catalyzes the hydrolysis of its 7 bound ATPs and releases the resulting Pi , which weakens the interactions binding GroES to GroEL

d) A second molecule of improperly folded substrate protein binds to the cis ring, followed by 7 ATP

e) The binding of substrate protein and ATP to the cis ring conformationally induces the trans ring to release its bound GroES, 7 ADP, and the presumably now better-folded substrate protein

Which of the following is incorrect functions of GroEL/ES chaperonin complex?