#Question id: 674
#Unit 1. Structure and Function of Biomolecules
Proline is not often found in a-helices of proteins because it
#Question id: 1520
#Unit 1. Structure and Function of Biomolecules
Following statements are regarding to enzymatic processing of benzo(a)pyrene to a more potent mutagen and carcinogen.
A. Liver enzymes, particularly P-450 enzymes, modify benzo(a)pyrene in a series of reactions, producing 7,8-diol-9,10-epoxide, a highly potent mutagenic species that reacts with DNA primarily at the N2 atom of a guanine base.
B. The adduct, (+)-trans-anti-B(a)P-N2-dG, causes polymerase to insert an A rather than a C opposite the modified G base. Next time the DNA is replicated, a T will be inserted opposite the A, and the mutation will be complete.
C. Potent mutagen majorly causes conversion of guanine (G) to thymine (T) bases, a transition mutation.
D. When this potent mutagen applied to cultured bronchial epithelial cells, activated benzo(a)pyrene induces many mutations, including activating mutations at codons 175, 248, and 273 of the p53 gene.
Which of the following statements are correct?
#Question id: 835
#Unit 1. Structure and Function of Biomolecules
The minor clefts and gullies on the sides of the funnel that will be false energy minima, it represents,
#Question id: 837
#Unit 1. Structure and Function of Biomolecules
Increasing order of free energy in unfolded to folded conformation of the proteins, the correct order is,
#Question id: 2636
#Unit 1. Structure and Function of Biomolecules
Which of the following events occur when E. coli is starved for tryptophan?
I. The ribosome translates leader peptide completely
II. Transcription reads through attenuator into trp EDCBA
III. Tryptophanyl tRNA is not formed
IV. A stem loop structure involving regions 3 and 4 is formed at attenuator site
#Question id: 18219
#Unit 1. Structure and Function of Biomolecules
