TLS Online TPP Program

#Question id: 568


Which of the following statements about allosteric control of enzymatic activity is false?

#Unit 1. Molecules and their Interaction Relevant to Biology
  1. Allosteric effectors give rise to sigmoidal V0 vs. [S] kinetic plots.

  2. Allosteric proteins are generally composed of several subunits.

  3. An effector may either inhibit or activate an enzyme.

  4. Heterotropic allosteric effectors compete with substrate for binding sites.

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TLS Online TPP Program

#Question id: 10308

#Unit 6. System Physiology – Plant

Oxidative decarboxylation of pyruvate to acetyl-CoA by the PDH complex, how the pyruvate dehydrogenase complex carries out the five consecutive reactions in the decarboxylation and dehydrogenation of pyruvate?

 A) Pyruvate reacts with the bound thiamine pyrophosphate (TPP) of pyruvate dehydrogenase, undergoing decarboxylation to the hydroxyethyl derivative

 B) A transesterification in which the —SH group of CoA replaces the —SH group of E2 to yield acetyl-CoA and the fully reduced (dithiol) form of the lipoyl group

 C) The reduced FADH2 of E3 transfers a hydride ion to NAD1 , forming NADH, the enzyme complex is now ready for another catalytic cycle

 D) The transfer of two electrons and the acetyl group from TPP to the oxidized form of the lipoyllysyl group of the core enzyme, dihydrolipoyl transacetylase, to form the acetyl thioester of the reduced lipoyl group

 E) Dihydrolipoyl dehydrogenase promotes transfer of two hydrogen atoms from the reduced lipoyl groups of E2 to the FAD prosthetic group of E3 , restoring the oxidized form of the lipoyllysyl group of E2

 Find out the correct sequence of action of this complex enzyme?

TLS Online TPP Program

#Question id: 938

#Unit 1. Molecules and their Interaction Relevant to Biology

Physiological roles for glutamate dehydrogenase include all of the following, except

TLS Online TPP Program

#Question id: 23244

#Unit 13. Methods in Biology

At which position does this piperidine cleaves?

TLS Online TPP Program

#Question id: 26367

#Unit 3. Fundamental Processes

Which one of the following protein is regulatory for triggering/transition  G1 to S phase or replication initiation

TLS Online TPP Program

#Question id: 28050

#Unit 1. Molecules and their Interaction Relevant to Biology

Which of the following does not lead to exposure of hydrophobic amino acids on the surface of a protein?