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TLS Online TPP Program

#Question id: 31029

All GPCR signal transduction pathways share the following common elements. which of the following is incorrect regarding GPCR? 

#Unit 4. Cell Communication and Cell Signaling
  1. A membrane-imbedded receptor that contains 7 TM α helices
  2. A heterotrimeric G protein, which functions as a receptor-activated switch 
  3. A cytosolic effector protein
  4. Proteins that participate in amplification and desensitization of the signaling pathway
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TLS Online TPP Program

#Question id: 28604

#Unit 2. Cellular Organization

What will cause the phosphorylation of T14 and Y15 in this G-loop?
a) It introduces negative charge that electrostatically interferes with the binding of ATP in the catalytic pocket
b) It introduces ionic bond interferes with the binding of ATP in the catalytic pocket
c) play a critical role in controlling CDK activity
d) Allows the binding of CDK with cyclins
Which of the following is correct about phosphorylation;
TLS Online TPP Program

#Question id: 28605

#Unit 2. Cellular Organization

Which of the following dual specificity kinases that involve to inhibits CDKs in all organisms?
TLS Online TPP Program

#Question id: 28606

#Unit 2. Cellular Organization

From T14 and Y15 remove inhibitory phosphate by___
TLS Online TPP Program

#Question id: 28607

#Unit 2. Cellular Organization

INK4s bind to CDK monomers, blocking their interaction with cyclin. At which phase of Cyclin and CDKs are inhibited by INK4?
TLS Online TPP Program

#Question id: 28608

#Unit 2. Cellular Organization

INK4 is__

a) Protooncogenes

b) Tumour suppressor gene

c) Undergo loss of function causes cancer

d) Undergo gain of function causes cancer
TLS Online TPP Program

#Question id: 28609

#Unit 2. Cellular Organization

A second class of CKIs found in metazoan cells is the Cip/Kip family of CKIs, consists of several CKIs proteins, except.