TLS Online TPP Program

#Question id: 7090


In what way, if any, does the chromosomal determination of sex differ in Drosophila and humans?

#Unit 5. Developmental Biology
  1. In humans, the Y chromosome determines maleness, with female development being a default state, but in Drosophila, the presence of two X chromosomes determines femaleness, and male development is the default state.
  2. In humans, the Y chromosome determines maleness, but in Drosophila, the ratio of X chromosomes to autosomes determines maleness or femaleness.
  3. In humans, it is the presence of only one X chromosome that triggers male development, and two X chromosomes trigger female development, just as occurs in Drosophila.
  4. In human males, a single Y chromosome is present in the absence of an X chromosome, while in Drosophila, a single X chromosome is present in the absence of a Y chromosome.

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TLS Online TPP Program

#Question id: 4283

#Unit 3. Fundamental Processes

Proteins can enter which organelle(s) in their folded conformation?

TLS Online TPP Program

#Question id: 4284

#Unit 3. Fundamental Processes

Assays for following the trafficking of proteins through the secretory pathway in living cells require

a. sensitive methods to distinguish the very small differences in organelle density caused by passage of a wave of protein transport through the organelle.

b. a way to identify compartments where labeled proteins are located.

c. the use of cell types that are highly dedicated secretory cells.

d. the use of enucleate cells in order to eliminate the nucleus as a site of labeling.

e. a way to label a cohort of secretory proteins

TLS Online TPP Program

#Question id: 4285

#Unit 3. Fundamental Processes

VSV G protein has been a very useful tracker protein for both living cell and in vitro assays because

TLS Online TPP Program

#Question id: 4286

#Unit 3. Fundamental Processes

Transport vesicles

a. can have a clathrin coat.     b. can be coated with a heteromeric COPI and COPII coat.

c. can contain assembly proteins.

d. can shuttle proteins from mitochondria to the endoplasmic reticulum.

e. can fuse with target organelles.

TLS Online TPP Program

#Question id: 4287

#Unit 3. Fundamental Processes

How the mTOR pathway increases the protein synthesis?

TLS Online TPP Program

#Question id: 4288

#Unit 3. Fundamental Processes

During eukaryotic protein synthesis, stress conditions result in activation of specific kinases leading to phosphorylation of a key translation initiation factor that inhibits protein synthesis from a large number of cellular mRNA. Which one of the following factors is the kinase?