TLS Online TPP Program

#Question id: 32315


What triggers the release of the LDL particle from its receptor in the endosome?

#Unit 2. Cellular Organization
  1. Dephosphorylation of the receptor
  2. Binding of ATP to the receptor
  3. Protonation of histidine residues in the β-propeller domain
  4. Degradation of apoB-100 in the endosome
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TLS Online TPP Program

#Question id: 7099

#Unit 5. Developmental Biology

A fate map of a Xenopus blastula, just before gastrulation begins, shows that the top portion of the embryo will become ectoderm (skin and nerve), the central portion will become mesoderm (bone, muscle, and blood), and the lowest portion will become endoderm (gut). How is it that the endoderm and mesoderm, shown on the outside in the fate map, end up on the inside in the embryo after gastrulation?

TLS Online TPP Program

#Question id: 7100

#Unit 5. Developmental Biology

If cells from the animal pole of a frog blastula (animal cap cells) are placed into contact with cells from the vegetal hemisphere, after removing the cells fated to form mesoderm, what is the result?

TLS Online TPP Program

#Question id: 7101

#Unit 5. Developmental Biology

What is the mechanism by which cells fated to be mesoderm form in the marginal zone of the Xenopus embryo?

TLS Online TPP Program

#Question id: 7102

#Unit 5. Developmental Biology

How is the Spemann organizer distinguished from the other mesodermal cells during induction by the cells of the vegetal region?

TLS Online TPP Program

#Question id: 7103

#Unit 5. Developmental Biology

Patterning of the Xenopus mesoderm along the dorso-ventral axis involves an antagonistic relationship between chordin and BMP-4. Is there an analogy here to dorso-ventral patterning in the Drosophila embryo?

TLS Online TPP Program

#Question id: 7104

#Unit 5. Developmental Biology

The grafting of the dorsal lip of the blastopore from an early Xenopus gastrula onto the ventral side of an early embryo will result in