The effects of pH on enzymes depends on a combination of factors: 

(a) Most enzymes are active within only a narrow pH range, typically 5 to 9. 

(b) the ionization states of the amino acid residues involved in the catalytic activity of the enzyme

(c) the variation of protein structure (usually significant only at extremes of pH).

Which of the above is correct

TLS Online TPP Program

#Question id: 16121

#Unit 7. System Physiology – Animal

 Match the following mechanisms (Column I) with their correct example (Column II).

Column I	Column II
A. Heat-generating and heat-retaining mechanisms	i. increased metabolic rate (thyroid hormones, sympathetic nervous system)
B. Heat-dissipating mechanisms	ii. vasodilation of blood vessels of the skin (decreased sympathetic tone)
	iii. increased activity of sympathetic cholinergic fibers to sweat glands.
	iv. shivering
	v. vasoconstriction of blood vessels of the skin (increased sympathetic tone)

TLS Online TPP Program

#Question id: 10806

#Unit 6. System Physiology – Plant

HCN is a fast-acting toxin that inhibits

TLS Online TPP Program

#Question id: 33504

#Unit 2. Cellular Organization

The techniques to identify the presence of exons can be based

A. Alignment algorithms 

B. Splicing reactions

C. Analysing ortholog

D. Zoo Blotting

TLS Online TPP Program

#Question id: 23897

#Unit 13. Methods in Biology

A microsatellite is a type of polymorphism that

TLS Online TPP Program

#Question id: 15652

#Unit 13. Methods in Biology

You are studying a new strain of E. coli that can utilize the disaccharide melibiose very efficiently. You find that utilization depends on the enzyme melibiase, which is encoded by the gene Mel1. Mel1 is not expressed unless melibiose is present in the growth medium. You have isolated a mutation that causes constitutive melibiase activity, which you designate MelA–. P1 phage mapping experiments using a Tn5 insertion linked to Mel1 show that MelA– is not linked to Mel1. Moreover you find that when an amber suppressor is introduced into a MelA– mutant, normal melibiase regulation is restored. Classify the MelA– mutation in terms of its basic genetic properties,