TLS Online TPP Program

#Question id: 7131


What is globin gene switching?

#Unit 5. Developmental Biology
  1. Globin gene switching refers to the switching on of the globin genes during erythrocyte differentiation.
  2. Globin gene switching refers to the switching from a-globin to b-globin, so that a2b2 hemoglobin can be made.
  3. Globin gene switching refers to the molecular basis for the genetic disease, sickle cell anemia.
  4. Globin gene switching refers to the transition, during fetal development, from the production of hemoglobin containing e-globin, to g-globin, to b-globin.
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TLS Online TPP Program

#Question id: 19164

#Unit 13. Methods in Biology

Affinity chromatography separation is based on

TLS Online TPP Program

#Question id: 1332

#Unit 4. Cell Communication and Cell Signaling

Desmosomes

TLS Online TPP Program

#Question id: 5409

#General Aptitude

The average of four consecutive even numbers is 49. The largest of these numbers is

TLS Online TPP Program

#Question id: 33453

#Unit 1. Molecules and their Interaction Relevant to Biology

The net charge on a nucleoside diphosphate is 

TLS Online TPP Program

#Question id: 2986

#Unit 2. Cellular Organization

During ubiquitin-mediated protein degradation in various events of cell cycle, ubiquitin-protein ligases ubiquitinylate substrate proteins, marking them for degradation by proteasomes. Cyclins are degraded through the action of two different ubiquitin-protein ligases, SCF and the anaphase-promoting complex or cyclosome. Following statements are regarding to SCF and APC/C.

A. SCF controls the G1–S phase transition by degrading G1/S phase cyclins and, CDK inhibitory proteins.

B. APC/C degrades S phase and mitotic cyclins, thereby promoting the exit from mitosis.

C. SCF and APC/C are multi-subunit ubiquitin-protein ligases that belong to the RING finger family of ubiquitin protein ligases.

D. SCF and APC/C belong to the different ubiquitin-protein ligase family, their regulation is same.

E. SCF recognizes its substrates only when they are phosphorylated.

F. SCF and APC/C both recognizes its substrates only when they are phosphorylated.

Which of the following is incorrect?