A. DNA is wrapped 1.67 times around the histone octamer.

B. The structure of the DNA is altered so that it has an increased number of base pairs/turn in the middle, but a decreased number at the ends.

C. 0.6 negative turns of DNA are absorbed by the change in bp/turn from 10.5 in solution 

D. 10.2 bp/turn on the nucleosomal surface is linking-number paradox.

Find true and false

#Question id: 4396

#Unit 3. Fundamental Processes

It is suspected that a novel protein only interacts with the promoter region of a gene. Which of the following techniques should be used to confirm this suspicion?

A. EMSA

B. DNase footprinting

C. Filter binding

D. Gel mobility shift assay

#Question id: 4397

#Unit 3. Fundamental Processes

Which of the following will prevent the activation of RNA polymerase, but not necessarily the assembly of eukaryotic general transcription factors at the promoter?

#Question id: 4398

#Unit 3. Fundamental Processes

Which of the following are not found in DNA-binding proteins?

#Question id: 4399

#Unit 3. Fundamental Processes

Transcription factors can

a. exhibit cooperative binding.  b. exist as heterodimers.

c. act to repress transcription of transcription factor genes.

d. undergo conformational changes which alter activity.

e. never interact with co-repressors.

#Question id: 4400

#Unit 3. Fundamental Processes

Which is the first factor to bind at the promoter of eukaryotic genes?

a. RNA polymerase

b. TFIIA

c. TFIIB

d. TFIID 

e. TATA box–binding protein

#Question id: 4401

#Unit 3. Fundamental Processes

Which of the following occur(s) during Pol II transcription preinitiation complex formation?

a. TFIIA binds to TFIIB.  b. TFIIB unwinds the DNA.

c. TFIIB contacts both TATA box–binding factor and DNA.

d. DNA bends.