TLS Online TPP Program

#Question id: 34134


A 45-year-old male with type 2 diabetes mellitus presents for routine follow-up. His fasting blood glucose is 110 mg/dL, but his HbA1c is 8.5%. Which of the following best explains the discrepancy between his fasting glucose and HbA1c?

#Unit 7. System Physiology – Animal
  1. The patient has anemia, reducing the lifespan of red blood cells and increasing HbA1c levels.
  2. The patient likely has frequent postprandial hyperglycemia despite normal fasting levels.
  3. HbA1c reflects glycemic control only in the 24–48 hours preceding measurement.
  4. Insulin therapy artificially increases HbA1c by promoting glycation of hemoglobin
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TLS Online TPP Program

#Question id: 4338

#Unit 3. Fundamental Processes

Altering patterns of gene expression in prokaryotes would most likely serve an organism's survival by __.

TLS Online TPP Program

#Question id: 4339

#Unit 3. Fundamental Processes

In positive control of several sugar metabolism-related operons, the cAMP receptor protein (CRP) binds to DNA to stimulate transcription. Which of the following environmental conditions causes an increase in CRP activity in stimulating transcription?

TLS Online TPP Program

#Question id: 4340

#Unit 3. Fundamental Processes

There is a mutation that is found in E. coli in the repressor that results in a molecule known as a super-repressor because it represses the lac operon permanently. Which of the following characteristics would you expect to observe in such a mutant?

TLS Online TPP Program

#Question id: 4341

#Unit 3. Fundamental Processes

Suppose an experimenter becomes proficient with a technique that allows her to move DNA sequences within a prokaryotic genome. If a researcher moves the promoter for the lac operon to the region between the beta galactosidase (lacZ) gene and the permease (lacY) gene, which of the following results would be most likely?

TLS Online TPP Program

#Question id: 4342

#Unit 3. Fundamental Processes

Suppose an experimenter becomes proficient with a technique that allows her to move DNA sequences within a prokaryotic genome. If a researcher moves the operator to the far end of the operon, past the transacetylase (lacA) gene, which of the following processes would likely occur when the cell is exposed to lactose?

TLS Online TPP Program

#Question id: 4343

#Unit 3. Fundamental Processes

Suppose an experimenter becomes proficient with a technique that allows her to move DNA sequences within a prokaryotic genome. If a researcher moves the repressor gene (lacI), along with its promoter, to a position at some several thousand base pairs away from its normal position, which of the following results would be expected?