TLS Online TPP Program

#Question id: 34134


A 45-year-old male with type 2 diabetes mellitus presents for routine follow-up. His fasting blood glucose is 110 mg/dL, but his HbA1c is 8.5%. Which of the following best explains the discrepancy between his fasting glucose and HbA1c?

#Unit 7. System Physiology – Animal
  1. The patient has anemia, reducing the lifespan of red blood cells and increasing HbA1c levels.
  2. The patient likely has frequent postprandial hyperglycemia despite normal fasting levels.
  3. HbA1c reflects glycemic control only in the 24–48 hours preceding measurement.
  4. Insulin therapy artificially increases HbA1c by promoting glycation of hemoglobin