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TLS Online TPP Program

#Question id: 34143

Which of the following best explains how normal plasma oxytocin levels at the onset of labor can still result in powerful uterine contractions?

#Unit 7. System Physiology – Animal
  1. The uterus begins secreting its own oxytocin, which inhibits progesterone and directly stimulates the fetal adrenal cortex.
  2. The descent of the fetus stimulates a hypothalamic feedback loop that rapidly increases systemic oxytocin to supraphysiologic levels.
  3. There is a marked upregulation of uterine oxytocin receptors at term, making the myometrium hypersensitive even to baseline oxytocin levels, initiating a positive feedback loop.
  4. Oxytocin receptors on the cervix and vagina directly stimulate the anterior pituitary to secrete oxytocin during early labor.
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TLS Online TPP Program

#Question id: 4511

#Unit 3. Fundamental Processes

The proteins are not needed for the splicing reaction itself, because
TLS Online TPP Program

#Question id: 4512

#Unit 3. Fundamental Processes

Some pre-mRNAs can be spliced in more than one way. Thus, mRNAs containing different selections of exons can be generated from a given pre-mRNA, called
TLS Online TPP Program

#Question id: 4513

#Unit 3. Fundamental Processes

Different snRNPs recognize the same (or overlapping) sequences in the pre-mRNA at different stages of the splicing reaction, which two snRNPs recognizing the 5’ splice site
TLS Online TPP Program

#Question id: 4514

#Unit 3. Fundamental Processes

What is true about coactivators,

A. The coactivators act directly by binding to the DNA

B. The coactivators act indirectly—not by binding to the DNA

C. Are required for essential communication between the activators and the complex composed of Pol II.

D. Are required for essential communication between the and the basal (or general) transcription factors.
TLS Online TPP Program

#Question id: 4515

#Unit 3. Fundamental Processes

Transcription Activators are,

A. Known to facilitate transcription at hundreds of promoters,

B. Specific for a few promoters,

C. Sensitive to the binding of signal molecules,

D. Providing the capacity to activate or deactivate transcription in response to a changing cellular environment.
TLS Online TPP Program

#Question id: 4516

#Unit 3. Fundamental Processes

High mobility group (HMG) proteins

A. are a common type of architectural regulator

B. facilitating the looping of the DNA

C. the binding is relatively very specific

D. are abundant in chromatin and bind to DNA with limited specificity.