Many proteins that act at the replication fork interact tightly. Which of the following interactions participate in DNA protein interactions

A. Sequence dependent interaction

B. Negative charge and structure of the phosphate backbone

C. Hydrogen-bonding residues in the minor groove for the palm domain

D. Hydrophobic stacking interactions between the bases for SSBs

Choose true and false

TLS Online TPP Program

#Question id: 28696

#Unit 2. Cellular Organization

N-linked oligosaccharide is attaching carbohydrate chain to the amide nitrogen of which amino acid residue?

TLS Online TPP Program

#Question id: 28697

#Unit 2. Cellular Organization

Biosynthesis of all N-linked oligosaccharides begins in the rough ER with a preformed branched oligosaccharide precursor containing_____

i) Glucose (Glc)

ii) Galactose

iii) Mannose (Man)

iv) N-acetylglucosamine (GlcNAc)

v) N-acetylgalactosamine (GalNAc)

TLS Online TPP Program

#Question id: 28698

#Unit 2. Cellular Organization

the oligosaccharide precursor is assembled on a membrane- attached anchor called dolichol phosphate, which is___

TLS Online TPP Program

#Question id: 28699

#Unit 2. Cellular Organization

First sugar residue is attached to dolichol by ___

TLS Online TPP Program

#Question id: 28700

#Unit 2. Cellular Organization

Biosynthesis of all N-linked oligosaccharides begins in the rough ER with a preformed branched oligosaccharide precursor Glc3Man9(GlcNAc)2, Which of the following statements is incorrect about these biosynthesis?

a) the oligosaccharide precursor is assembled on a membrane- attached anchor called dolichol phosphate

b) First sugar residue is attached to dolichol by a glycosidic bonds & the other

sugars are added by high-energy pyrophosphate

c) Two N- acetylglucosamine (GlcNAc) and five mannose residues are added one at a time to a dolichol phosphate on the lumen

d) Four mannose and three glucose  residue are added one to a dolichol phosphate on the luminal side

TLS Online TPP Program

#Question id: 28701

#Unit 2. Cellular Organization

Which of the following inhibitors inhibits the synthesis of all N-linked oligosaccharides in cells?