Following statements are regarding to convergent extension of the dorsal mesoderm in xenopus.

A. For convergent extension the first force is a polarized cell cohesion wherein the involuted mesodermal cells intercalate and the second force is differential cell cohesion.

B. The intercalations of mesodermal cells, both mediolaterally and radially, are stabilized by the planar cell polarity (PCP) pathway that is initiated by Wnts independent of β-catenin signaling.

C. The intercalations of mesodermal cells, are stabilized by the planar cell polarity (PCP) pathway that is initiated by Wnts dependent of β-catenin signaling.

D. Another factor regulating convergent extension is calcium influx from environment.

E. Ca2+ is released from intracellular stores and is required for convergent extension.

Which of the following combination is correct?

#Question id: 650

#Unit 1. Molecules and their Interaction Relevant to Biology

On the basis of hypothetical binding curve given below, which of the following statement is INCORRECT

#Question id: 651

#Unit 1. Molecules and their Interaction Relevant to Biology

Consider an enzyme catalysed reaction treated with inhibitor. Enzyme kinetic was analysed with Eadie Hofstee equation. A plot of V0 versus V0/[S] for an enzyme-catalyzed reaction is shown below. The control curve was obtained in the absence of inhibitor. Which effect is shown on the enzyme activity when an inhibitor is added to the reaction mixture?

#Question id: 652

#Unit 1. Molecules and their Interaction Relevant to Biology

Two proteins, X and Y, bind to the same ligand, A, with the binding curves shown below. Which of the statement is correct for the graph analysing two proteins?

#Question id: 653

#Unit 1. Molecules and their Interaction Relevant to Biology

For the enzyme-catalyzed reaction S ~ P, Keq = 5, which of the following curves best represents the change in [S] that occurs with time when S is added to a solution containing the appropriate enzyme?

#Question id: 653

#Unit 1. Molecules and their Interaction Relevant to Biology

For the enzyme-catalyzed reaction S ~ P, Keq = 5, which of the following curves best represents the change in [S] that occurs with time when S is added to a solution containing the appropriate enzyme?

#Question id: 654

#Unit 1. Molecules and their Interaction Relevant to Biology

Which pair represents different conformations?