TLS Online TPP Program

#Question id: 7218


Following statements are regarding to convergent extension of the dorsal mesoderm in xenopus.

A. For convergent extension the first force is a polarized cell cohesion wherein the involuted mesodermal cells intercalate and the second force is differential cell cohesion.

B. The intercalations of mesodermal cells, both mediolaterally and radially, are stabilized by the planar cell polarity (PCP) pathway that is initiated by Wnts independent of β-catenin signaling.

C. The intercalations of mesodermal cells, are stabilized by the planar cell polarity (PCP) pathway that is initiated by Wnts dependent of β-catenin signaling.

D. Another factor regulating convergent extension is calcium influx from environment.

E. Ca2+ is released from intracellular stores and is required for convergent extension.

Which of the following combination is correct?

#Unit 5. Developmental Biology
  1. A, B and C
  2. A, B and D
  3. A, B and E
  4. A and D only