TLS Online TPP Program

#Question id: 785


Several types of very short RNAs repress—or silence—expression of genes with homology to those short RNAs. They are produced from a variety of sources and direct the silencing of genes in the following different ways-

#Unit 1. Molecules and their Interaction Relevant to Biology
  1. Triggering destruction of the mRNA encoded by the target gene

  2. Inhibiting translation of the mRNA

  3. Inducing chromatin modifications within the target gene and thereby silencing its transcription

  4. All of the above

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TLS Online TPP Program

#Question id: 12997

#Unit 1. Molecules and their Interaction Relevant to Biology

Which of the given reason is correct to minimize the repulsion in an α-helix
a) positively charged amino acids are often found near the amino terminus of the helical segment
b) negatively charged amino acids are often found near the amino terminus of the helical segment
c) positively charged amino acids are often found near the C-terminus of the helical segment.
d) negatively charged amino acids are often found near the C-terminus of the helical segment.

TLS Online TPP Program

#Question id: 12998

#Unit 1. Molecules and their Interaction Relevant to Biology

Match with appropriate bonding pattern

Helix typeHydrogen bonding
a. α-helix1. n, n+3
b. 310 helix2. n, n+5
c. π helix3. n, n+4

TLS Online TPP Program

#Question id: 12999

#Unit 1. Molecules and their Interaction Relevant to Biology

Proline and glycine both disturb the symmetry of α-helix which of the following are true regarding to these two amino acids
a) proline changes the orientation of hetropolymeric α-helix hence proline can be placed only as 1st amino acid residue near to C-terminus 
b) proline changes the orientation of polymeric α-helix hence proline can be placed only as 1st amino acid residue near to N-terminus
c) glycine disrupts the heteropolymeric α-helix by changing the helicity.
d) homopolymer of proline and glycine can form stable helix. 

TLS Online TPP Program

#Question id: 13000

#Unit 1. Molecules and their Interaction Relevant to Biology

Identify the correct statement regarding the structure


TLS Online TPP Program

#Question id: 13001

#Unit 1. Molecules and their Interaction Relevant to Biology

Which of the following is incorrect 
a) antiparallel β sheets are frequently found and they are quite more stable because of more no. hydrogen bond presence and linear H bonding pattern.
b) antiparallel β sheets are frequently found and they are quite more stable because of more no. hydrogen bond presence and having distorted H bonding pattern.
c) parallel β sheets are relatively less stable and mostly found in core of protein.
d) parallel β sheets are relatively more stable and mostly found in core of protein.

TLS Online TPP Program

#Question id: 13002

#Unit 3. Fundamental Processes

Where in a eukaryotic cell do you think you would find each of the following proteins residing when it is actively performing its function. Be as specific as you can in terms of subcellular location.
Match the following with the correct subcellular location;
Column 1Column 2
I) Polymerasesa) In the cytoplasm
II) Ribosomal proteinsb) Inside the plasma membrane.
III) DNA ligasec) In the mitochondrial matrix
IV) protein that allows ions to pass in and out of the celld) In the nucleus of cells
V) Activator proteine) Inside the nuclear membrane
VI) an enzyme in the Krebs/TCA cycle
VII) a protein that forms a channel through which mRNAs can be exported into the cytoplasm